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Christian Hassager Selected Research

Induced Hypothermia

9/2022Comparing Doppler Echocardiography and Thermodilution for Cardiac Output Measurements in a Contemporary Cohort of Comatose Cardiac Arrest Patients Undergoing Targeted Temperature Management.
6/2022Targeted temperature management after out of hospital cardiac arrest: quo vadis?
1/2022Electrolyte profiles with induced hypothermia: A sub study of a clinical trial evaluating the duration of hypothermia after cardiac arrest.
11/2021Treatment Effects of Interleukin-6 Receptor Antibodies for Modulating the Systemic Inflammatory Response After Out-of-Hospital Cardiac Arrest (The IMICA Trial): A Double-Blinded, Placebo-Controlled, Single-Center, Randomized, Clinical Trial.
11/2021Increasing mean arterial pressure or cardiac output in comatose out-of-hospital cardiac arrest patients undergoing targeted temperature management: Effects on cerebral tissue oxygenation and systemic hemodynamics.
9/2021Impact of Hypothermia on Oxygenation Variables and Metabolism in Survivors of Out-of-Hospital Cardiac Arrest Undergoing Targeted Temperature Management at 33°C Versus 36°C.
7/2021Factors Associated With Rebound Hyperthermia After Targeted Temperature Management in Out-of-Hospital Cardiac Arrest Patients: An Explorative Substudy of the Time-Differentiated Therapeutic Hypothermia in Out-of-Hospital Cardiac Arrest Survivors Trial.
1/2021Repolarization and ventricular arrhythmia during targeted temperature management post cardiac arrest.
11/2020Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest.
11/2020Arterial blood pressure during targeted temperature management after out-of-hospital cardiac arrest and association with brain injury and long-term cognitive function.
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Christian Hassager Research Topics

Disease

91Out-of-Hospital Cardiac Arrest
12/2022 - 02/2009
54Heart Arrest (Cardiac Arrest)
10/2022 - 01/2006
37Coma (Comas)
09/2022 - 01/2006
19ST Elevation Myocardial Infarction
04/2021 - 01/2015
18Heart Failure
11/2021 - 09/2004
16Myocardial Infarction
11/2021 - 01/2005
15Cardiogenic Shock
11/2021 - 03/2014
13Inflammation (Inflammations)
12/2021 - 11/2014
12Stroke (Strokes)
12/2021 - 08/2010
11Brain Injuries (Brain Injury)
12/2022 - 01/2019
9Endocarditis
10/2019 - 01/2009
8Hypothermia
01/2022 - 09/2012
8Shock
08/2021 - 09/2014
7Systolic Heart Failure
01/2022 - 02/2011
6Cardiac Arrhythmias (Arrythmia)
07/2021 - 08/2012
6Atrial Fibrillation
01/2021 - 12/2012
6Left Ventricular Dysfunction
05/2020 - 01/2008
5Hemorrhage
12/2021 - 10/2003
5Post-Cardiac Arrest Syndrome
11/2021 - 01/2016
5Ischemia
01/2020 - 04/2016
5Aortic Valve Stenosis (Aortic Stenosis)
01/2018 - 10/2003
4Acute Kidney Injury (Acute Renal Failure)
07/2021 - 10/2018
4Infarction (Infarctions)
01/2021 - 08/2010
3Brain Ischemia (Cerebral Ischemia)
12/2020 - 01/2019
3Cardiac Sudden Death (Sudden Cardiac Arrest)
11/2020 - 06/2017
3Hypertension (High Blood Pressure)
04/2014 - 08/2010
2Wounds and Injuries (Trauma)
08/2022 - 04/2022
2Postoperative Cognitive Complications
01/2022 - 06/2020
2COVID-19
12/2021 - 11/2021
2Infections
12/2021 - 09/2013
2Hypotension (Low Blood Pressure)
12/2021 - 01/2020
2Hypoxia (Hypoxemia)
12/2021 - 12/2007
2Type 2 Diabetes Mellitus (MODY)
11/2021 - 12/2016
2Acute Coronary Syndrome
08/2021 - 01/2020
2Critical Illness (Critically Ill)
01/2021 - 01/2020
2Myocardial Ischemia (Ischemic Heart Diseases)
09/2020 - 01/2017
2Cerebral Infarction
06/2020 - 01/2015
2Bundle-Branch Block (Fascicular Block)
01/2019 - 09/2004
2Reperfusion Injury
12/2016 - 01/2016
2Bradycardia
02/2016 - 04/2015
2Thrombosis (Thrombus)
11/2015 - 03/2014
2Ventricular Fibrillation
06/2009 - 01/2006
1Severe Acute Respiratory Syndrome
12/2021
1Renal Insufficiency (Renal Failure)
11/2021
1Hyperthermia
07/2021

Drug/Important Bio-Agent (IBA)

32Biomarkers (Surrogate Marker)IBA
12/2022 - 12/2014
11Lactic Acid (Lactate)FDA LinkGeneric
03/2021 - 09/2014
8Phosphopyruvate Hydratase (Enolase)IBA
10/2022 - 05/2015
7MicroRNAs (MicroRNA)IBA
08/2022 - 02/2015
7Brain Natriuretic Peptide (Natrecor)FDA Link
11/2021 - 06/2008
5Glucagon-Like Peptide 1 (GLP 1)IBA
11/2021 - 01/2016
4Troponin T (Troponin T1)IBA
11/2021 - 12/2012
4C-Reactive ProteinIBA
11/2021 - 01/2017
4Interleukin-6 (Interleukin 6)IBA
11/2021 - 06/2015
4pro-brain natriuretic peptide (1-76)IBA
05/2020 - 10/2012
4Exenatide (Byetta)FDA Link
01/2018 - 01/2016
4Neuroprotective AgentsIBA
01/2017 - 11/2015
3cytidylyl-(3'-5')-cytidine (CpC)IBA
12/2022 - 02/2009
3Oxygen (Dioxygen)IBA
02/2022 - 01/2019
3Glial Fibrillary Acidic ProteinIBA
01/2022 - 01/2019
3TroponinIBA
12/2021 - 10/2012
3Proteins (Proteins, Gene)FDA Link
01/2021 - 10/2018
3AdrenomedullinIBA
09/2020 - 01/2020
3Blood Glucose (Blood Sugar)IBA
09/2020 - 08/2017
3Gentamicins (Gentamicin)FDA LinkGeneric
04/2013 - 01/2009
3Sildenafil Citrate (Viagra)FDA Link
04/2013 - 12/2007
2Calcium-Binding ProteinsIBA
10/2022 - 12/2017
2ElectrolytesIBA
01/2022 - 09/2013
2Norepinephrine (Noradrenaline)FDA LinkGeneric
11/2021 - 08/2020
2Interleukin-6 Receptors (Interleukin 6 Receptor)IBA
11/2021 - 10/2020
2tocilizumab (atlizumab)FDA Link
11/2021 - 10/2020
2AntibodiesIBA
11/2021 - 10/2020
2Complement System Proteins (Complement)IBA
11/2020 - 01/2019
2Atrial Natriuretic Factor (ANF)IBA
09/2020 - 09/2020
2Epoprostenol (Prostacyclin)FDA LinkGeneric
01/2020 - 01/2016
2CatecholaminesIBA
11/2018 - 01/2016
2ThrombomodulinIBA
11/2018 - 01/2015
2ProcalcitoninIBA
01/2017 - 06/2015
2Simvastatin (Zocor)FDA LinkGeneric
10/2013 - 04/2008
1Angiotensin-Converting Enzyme 2IBA
12/2021
1CytokinesIBA
12/2021
1MB Form Creatine KinaseIBA
11/2021
1Amiodarone (Amiodarona)FDA LinkGeneric
07/2021
1MagnesiumIBA
07/2021
1Fondaparinux (Arixtra)FDA Link
04/2021

Therapy/Procedure

61Induced Hypothermia
09/2022 - 01/2006
31Resuscitation
04/2022 - 06/2009
21Therapeutics
10/2021 - 09/2004
13Percutaneous Coronary Intervention
08/2021 - 12/2012
12Implantable Defibrillators (Implantable Cardioverter-Defibrillator)
01/2022 - 12/2013
9Critical Care (Surgical Intensive Care)
12/2021 - 10/2018
6Cardiac Resynchronization Therapy
01/2016 - 09/2004
5Renal Replacement Therapy (Therapies, Renal Replacement)
12/2021 - 09/2013
5Cardiopulmonary Resuscitation (CPR)
07/2021 - 06/2009
4Coronary Artery Bypass (Coronary Artery Bypass Surgery)
01/2021 - 01/2008
3Defibrillators (Defibrillator)
01/2022 - 01/2016
3Rewarming
07/2021 - 04/2016
3Length of Stay
01/2021 - 02/2007
2Catheters
09/2022 - 12/2021
2Heart-Assist Devices
07/2021 - 06/2021